Baclofen Receptors
《英文msh詞典》Baclofen Receptors
[同義詞] Baclofen Receptors
[主題詞] Receptors,GABA-B
[中文釋義] 巴氯芬受體
[英文釋義] Cell surface proteins which bind GAMMA-AMINOBUTYRIC ACID and influence cells via interactions with G-proteins. GABA-B receptors are pharmacologically characterized by their insensitivity to the blocker bicuculline and sensitivity to the agonist L-baclofen. They are found both presynaptically and postsynaptically,and act variously by inhibition of adenylate cyclase,activation of phospholipase A2,activation of potassium channels,and inactivation of voltage-activated calcium channels.